Chylous ascites: treated with total parenteral nutrition and somatostatin.

Huang Q, Jiang ZW, Jiang J, Li N, Li JS.

Institute of General Surgery, Jinling Hospital, 305 Zhongshan East Road, Nanjing 210002, Jiangsu Province, China.

AIM: To determine the effects of total parenteral nutrition and somatostatin on patients with chylous ascites. METHODS: Five patients were diagnosed with chylous ascites on the basis of laboratory findings of ascites sample from Nov 1999 to May 2003. Total parenteral nutrition and somatostatin or its analogue was administered to 4 patients, while the other one only received total parenteral nutrition. All the patients had persistent peritoneal drainage, with the quantity and quality of drainage fluid observed daily. Necessary supportive treatments were given to the patients individually during the therapy. RESULTS: Two of 4 patients who received somatostatin therapy obtained complete recovery within 10 d without any recurrence while on a normal diet. In these 2 patients, the peritoneal drainage reduced to zero in one and the other's decreased from 2,000 mL to 80 mL with a clear appearance and negative qualitative analysis of chyle. Recurrent chylous ascites, though relieved effectively by the same method every time, developed in one patient with advanced pancreatic cancer. The other patient's lymphatic fistula was blocked with the fibrin glue after conservative treatment. The patient who only received total parenteral nutrition was cured 24 d after therapy. CONCLUSION: Total parenteral nutrition along with somatostatin can relieve the symptoms and close the fistula in patients with chylous ascites rapidly. It appears to be an effective therapy available for the treatment of chylous ascites caused by various disorders. Copyright 2004 The WJG Press ISSN

Ganz kurze stümperhafte Kurzzusammenfassung nach meinem Verständnis:
Es fand eine Studie statt mit Personen, die eine Drainage wegen Ascites haben und künstlich ernährt werden. Einige bekamen nur die Ernährung, andere künstl. Ernährung und Somatostatin. Die Gruppe mit Somatostatin zeigte sehr gute Erfolge.
Künstl. Ernährung (parenterale Ernährung, z.B. über Port) zusammen mit Somatostatin kann die Symptome verbessern und die Fisteln schnell schließen. Es erscheint eine wirkungsvolle Therapie für die Behandlung von (chylous?) Aszites hervorgerufen durch verschiedene Störungen zu sein.